Medicago Sp. - Alfalfa
Family: Pea - Fabaceae [E-flora]
"Annual, perennial herb, unarmed, generally hairy. Stem: prostrate to erect. Leaf: subpalmately compound or generally odd-1-pinnate; stipules ± fused to petiole, entire or deeply cut; leaflets 3, generally dentate near tip. Inflorescence: axillary or terminal, raceme, generally umbel- or ± head-like, 1–many-flowered. Flower: calyx lobes ± equal or not; corolla yellow or purple; 9 filaments fused, 1 free. Fruit: indehiscent, reniform or generally spirally coiled 1.5–8 turns (or sickle-shaped or straight), generally prickly. Seed: 1–several.
83 species: Mediterranean to western and central Asia; several cultivated, naturalized in warm temperate. (Greek: Medice, now Media, Asia Minor, source of alfalfa) Medicago muricata possibly naturalized in Carrizo Plain." [Jepson]
Local Species;
- Medicago arabica - spotted medic [E-flora]
- Medicago lupulina - black medic [E-flora]
- Medicago polymorpha - bur-clover [E-flora]
- Medicago sativa - alfalfa [E-flora]
Uses of Other Medicago Sp.
- Medicago denticulata Willd. "North temperate region of the Old World. A fine, broad-leaved variety of this plant was found by Fortune to be much used by the Chinese as a winter vegetable" "North temperate region of the Old World; naturalized in places in America. In southern California, its seeds are much relished by the Indians." [Sturtevant EPW]
- M. platycarpa Trautv." Siberia. The plant furnishes a food." [Sturtevant EPW]
- M. scutellata Mill. "Mediterranean region. This plant is not edible but, like the caterpillarplant, is grown on account of the singular shape of its seed-vessels. It was in Belgian and German gardens preceding 1616 and in American gardens in 1863 or before." [Sturtevant EPW]
| Medicago arborea | |
| Tumor (Hartwell) [DukePhyt] | |
| Medicago lupulina | |
| Bactericide (Woi.Syria); Lenitive (Woi.Syria) [DukePhyt] | |
| Medicago sp | |
| Cancer (Hartwell) [DukePhyt] | |
Medicago polymorpha L., Bur Clover
Medicago sativa L., Alfalfa . Drug--{:,ostanoan Ear Medicine Poultice of heated leaves applied to the ear for earaches. (21:19)
|
References
- [DukePhyt]Accessed March 2, 2015
- [Jepson] Martin F. Wojciechowski & Duane Isely, 2013. Medicago, in Jepson Flora Project (eds.) Jepson eFlora, http://ucjeps.berkeley.edu/cgi-bin/get_IJM.pl?tid=9375, accessed on Feb 21 2015
Medicago arabica - spotted medic
"General: Annual herb; stems prostrate or decumbent, 30-80 cm tall, nearly glabrous or with long soft hairs." [IFBC-E-flora]
Origin Status: Exotic [E-flora]
Habitat / Range"Mesic to dry fields and waste places; rare, known only from the Victoria area; introduced from Eurasia." [IFBC-E-flora]
Synonyms
- Medicago arabica subsp. inermis Ricker
- Medicago maculata Sibth. [E-flora]
- http://linnet.geog.ubc.ca/Atlas/Atlas.aspx?sciname=Medicago%20arabica&redblue=Both&lifeform=7, Accessed March 1, 2015
Medicago lupulina - black medic
"Medicago lupulina is a ANNUAL/PERENNIAL growing to 0.5 m (1ft 8in) at a medium rate.
It is hardy to zone (UK) 5 and is not frost tender. It is in flower from Apr to August, and the seeds ripen from Jul to September. The flowers are hermaphrodite (have both male and female organs) and are pollinated by Bees, lepidoptera, self.The plant is self-fertile.
It can fix Nitrogen.
Suitable for: light (sandy), medium (loamy) and heavy (clay) soils and prefers well-drained soil. Suitable pH: acid, neutral and basic (alkaline) soils. It cannot grow in the shade. It prefers moist soil." [PFAF]
Origin Status:Exotic [E-flora]
"General: Annual or sometimes short-lived perennial herb; stems prostrate to erect, 10-50 cm long, branched from the base, downy." [IFBC-E-flora]
Habitat / Range
"Mesic to dry fields, roadsides and waste places; common in BC S of 56degreeN, rare on the Queen Charlotte Islands, absent on N Vancouver Island; introduced from Eurasia." [IFBC-E-flora] "Grassy places and roadsides[17], often occurring as a garden weed on acid and calcareous soils[1]. Europe, including Britain, south and east to N. Africa, the Atlantic Islands and W. Asia." [PFAF]
This clover is widely distributed as a weed over most of the United States. [EWP]
- Seeds
- The Indians of southern California greatly relish the seeds. [EWP]
"Seed - cooked[2, 105, 161]. Parched and eaten or ground into a powder[183]. The seed is said to contain trypsin inhibitors[218]. These can interfere with certain enzymes that help in the digestion of proteins, but are normally destroyed if the seed is sprouted first." [PFAF]
- The Indians of southern California greatly relish the seeds. [EWP]
- Leaves
- "Leaves - cooked[105]. Used as a potherb[183]. A nutritional analysis is available[218]." [PFAF]
- "Leaves - cooked[105]. Used as a potherb[183]. A nutritional analysis is available[218]." [PFAF]
Medicinal Uses
"Aqueous extracts of the plant have antibacterial properties against micro-organisms[218, 240]. The plant is lenitive[218, 240]." [PFAF]
Nutritional
Figures in grams (g) or miligrams (mg) per 100g of food. Leaves (Dry weight)
- 0 Calories per 100g
- Water : 0%
- Protein: 23.3g; Fat: 3.3g; Carbohydrate: 0g; Fibre: 24.7g; Ash: 10.3g;
- Minerals - Calcium: 1330mg; Phosphorus: 300mg; Iron: 0mg; Magnesium: 450mg; Sodium: 0mg; Potassium: 2280mg; Zinc: 0mg;
- Vitamins - A: 0mg; Thiamine (B1): 0mg; Riboflavin (B2): 0mg; Niacin: 0mg; B6: 0mg; C: 0mg;
- Reference: [ 218] [PFAF]
Propagation
"Pre-soak the seed for 12 hours in warm water and then sow in spring in situ[200]. The seed can also be sown in situ in autumn. Green manure crops can be sown in situ from early spring until early autumn[87]. (the later sowings are for an over-wintering crop)" [PFAF]
Cultivation
"A good green manure plant, it is fairly deep rooted, has good resistance to 'Clover rot' but it is not very fast growing[87]. It can be undersown with cereals, succeeding even in a wet season[87]." [PFAF]
"Dislikes acid soils[87]. (This conflicts with the notes on its habitat above.) Dislikes shade. A good food plant for many caterpillars[30]. This species has a symbiotic relationship with certain soil bacteria, these bacteria form nodules on the roots and fix atmospheric nitrogen. Some of this nitrogen is utilized by the growing plant but some can also be used by other plants growing nearby[200]." [PFAF]
Synonyms
- Medicago lupulina var. cupaniana (Guss.) Boiss.
- Medicago lupulina var. glandulosa Neilr. [E-flora]
- [E-flora] http://linnet.geog.ubc.ca/Atlas/Atlas.aspx?sciname=Medicago%20lupulina&redblue=Both&lifeform=7, Accessed March 2, 2015
- [PFAF] http://www.pfaf.org/user/Plant.aspx?LatinName=Medicago+lupulina Accessed Dec 13, 2014
- [UMD-Eth]
Medicago polymorpha - bur-clover
Origin Status: Exotic[E-flora]
"General: Annual herb; stems prostrate to erect, 10-50 cm long/tall, glabrous or sparsely short-hairy." [IFBC-E-flora]
Habitat / Range: "Mesic to dry fields and waste places, often with sandy or gravelly soil; rare in SW BC; introduced from Eurasia."[IFBC-E-flora]References
- http://linnet.geog.ubc.ca/Atlas/Atlas.aspx?sciname=Medicago%20polymorpha&redblue=Both&lifeform=7, Accessed March 2, 2015
Medicago sativa - alfalfa
"Medicago sativa is a PERENNIAL growing to 1 m (3ft 3in) at a medium rate.
It is hardy to zone (UK) 5. It is in flower from Jun to July, and the seeds ripen from Jul to September. The flowers are hermaphrodite (have both male and female organs) and are pollinated by Bees, lepidoptera, self.The plant is self-fertile. It can fix Nitrogen.
It is noted for attracting wildlife.
Suitable for: light (sandy), medium (loamy) and heavy (clay) soils, prefers well-drained soil and can grow in nutritionally poor soil. Suitable pH: acid, neutral and basic (alkaline) soils. It cannot grow in the shade. It prefers dry or moist soil and can tolerate drought." [PFAF]
Introduction
"now cultivated extensively throughout the world. The species has several distinct variants including M. sativa (sensu stricto) and subsp. falcata (L.) Arcangeli (syn. M. falcata L.). The former is a purple-flowered form with strongly coiled legumes, originating from an arid continental climate in alkaline soils, principally from Turkey. Wild and cultivated M. sativa subsp. sativa and their progeny are relatively low in hemolytic saponins. M. sativa subsp. falcata has yellow flowers and uncoiled fruits, originating from cool, upland, humid climates in acidic soils and is comparatively higher in hemolytic saponins. Both taxa are involved in the parentage of numerous commercial alfalfa cultivars.[1] Modern western European and North American cultivars have intermediate levels of hemolytic alfalfa saponins due to hybridization and introgressions involving M. sativa subsp. falcata.[2]" [Leung ENCI]
SUBTAXA PRESENT IN BC
- Medicago sativa ssp. falcata
- Medicago sativa ssp. sativa [E-flora]
"General: Perennial herb from a long taproot; stems erect to decumbent, 30-100 cm tall/long, slender, finely stiff-hairy to glabrous. [IFBC-E-flora]
Habitat / Range: "Mesic to dry cultivated fields, roadsides and ditches (ssp. sativa), and roadsides and dry slopes (ssp. falcata) in the steppe zone; ssp. sativa - common agricultural escape in S BC west of the Coast-Cascade Mountains, infrequent in SW BC, ssp. falcata - rare, known from scattered locations in S BC; introduced from Eurasia." [IFBC-E-flora]
"Waste ground, avoiding acid soils[17].Europe - Mediterranean. More or less naturalized in Britain[17]." [PFAF]
Origin Status: Exotic [E-flora]Hazards
"The chemistry of alfalfa is well documented and it does appear to be a good source of vitamins and minerals, thereby supporting the herbal uses. However, normal human dietary intake of alfalfa is low and excessive ingestion should be avoided in view of the many pharmacologically active constituents (e.g. canavanine, isoflavones and saponins), which may give rise to unwanted effects if taken to excess."[HerbalMed3]
"Alfalfa should not be recommended for the treatment of arthritis. Coumarin compounds detected so far in alfalfa do not possess the minimum structural requirements for anticoagulant activity."[HerbalMed3]
"In view of the documented pharmacological actions of alfalfa the potential for preparations of alfalfa to interfere with those of other medicines administered concurrently, particularly those with similar or opposing effects, such as medicines with hormonal activity, should be considered."[HerbalMed3]
"Alfalfa seeds are reputed to affect the menstrual cycle and to be lactogenic. Although the safety of alfalfa herb has not been established, it is probably acceptable for use during pregnancy and lactation provided that doses do not exceed the amounts normally ingested as a food. Alfalfa seeds should not be ingested during pregnancy or lactation."[HerbalMed3]
"Canavanine is known to be toxic to all animal species because it is a structural analogue of arginine and may interfere with the binding of this amino acid to enzymes and its incorporation into proteins. Alfalfa seeds are reported to contain substantial quantities of canavanine (8.33–13.6 mg/kg), whereas the herb contains considerably less."[HerbalMed3]
"Pancytopenia [a medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets] has been associated with human ingestion of ground alfalfa seeds (80–160 g/day), which were taken to lower plasma cholesterol concentrations."[HerbalMed3]
"The plant contains saponin-like substances[222]. Eating large quantities of the leaves may cause the breakdown of red blood cells[222]. However, although they are potentially harmful, saponins are poorly absorbed by the human body and so most pass through without harm. Saponins are quite bitter and can be found in many common foods such as some beans. Thorough cooking, and perhaps changing the cooking water once, will normally remove most of them from the food. Saponins are much more toxic to some creatures, such as fish, and hunting tribes have traditionally put large quantities of them in streams, lakes etc in order to stupefy or kill the fish[K]. Alfalfa sprouts (and especially the seeds) contain canavanine. Recent reports suggest that ingestion of this substance can cause the recurrence of systemic lupus erythematosus (an ulcerous disease of the skin) in patients where the disease had become dormant[222]. The FDA advises that children, the elderly and people with compromised immune systems should avoid eating alfalfa sprouts due to bacterial contamination. Avoid during pregnancy and lactation. Avoid for people with hormone sensitive cancer. Avoid for people with gout (due to purines). Possible antagonize the anticoagulant effect of warfarin (due to vit K) and interfere with the immunosuppressant effect of corticosteroids [301]." [PFAF]
"Some caution is advised in the use of this plant, however. It should not be prescribed to people with auto-immune diseases such as rheumatoid arthritis[238]." [PFAF]
"Stachydrine and l-homostachydrine, in the seeds, may be emmenagogue and lactogenic. One patient died from listerosis after ingesting contaminated alfalfa tablets (LRNP, March 1991). Seeds and/or sprouts may contain 13,000 ppm canavanine, which may be implicated in hypocomplementenemia, lupus, and pancytopenia. Canavanine, a toxic amino acid, may cause systemic lupus erythematosus syndrome (CAN). Systemic lupus erythematosus (SLE)-like manifestations, skin reactions, gastrointestinal disturbances, raised serum urate levels are symptoms that have been associated with alfalfa use in humans. Seeds should not be ingested during pregnancy or lactation (CAN). May cause stomach upset and diarrhea. Believed by some herbalists to be helpful in delaying absorption of cholesterol and dissolving plaque deposits on arterial walls (TMA). Consumption of alfalfa tablets contaminated with Listeria monocytogenes was linked to a fatal case of listerosis. One case of allergic reaction (from contamination with grass pollen) in alfalfa tablets has been reported (SF2). Flatulence, abdominal discomfort, loose stools, diarrhea, and loss of appetite may result from ingesting large amounts of alfalfa seeds (120 g/day)." [HMH Duke]
- "People with a history of lupus or a family history of systemic lupus erythematosus should avoid M. sativa supplements (Barnes et al. 2007; Boon & Smith, 2004; Brinker, 2001)" [MedicagoSativa].
- "M. sativa seeds should not be ingested during pregnancy or lactation (Brinker, 2001)" [MedicagoSativa]
- Diabetes: "Alfalfa may affect blood sugar concentrations in diabetic patients because of the manganese content."[HerbalMed3]
"Although it has been suggested that alfalfa may interact with antidiabetic medicines and anticoagulants, evidence for this is largely lacking. Alfalfa may interact with immunosuppressants, and has apparently caused transplant rejection in one patient. Potential interactions of specific isoflavone constituents of alfalfa are covered under isoflavones" [HMI Stockey]
- "For discussion of a study showing that daidzein and genistein present in alfalfa caused a minor decrease in the metabolism of nicotine, see Isoflavones + Nicotine, page 261."[HMI Stockey]
- "No data for alfalfa found. For the possibility that high-dose biochanin A, an isoflavone present in alfalfa, might increase digoxin levels, see Isoflavones + Digoxin, page 261."[HMI Stockey]
- "Alfalfa + Warfarin and related drugs"[HMI Stockey]
Edible Uses
- Leaves & Young Shoots
- "Raw or cooked[2, 8, 52, 145]. The leaves can also be dried for later use[55]. Very rich in vitamins[183], especially A, B and C[201], they are also a good source of protein[206]. The leaves are a rich source of vitamin K[213]. A very nutritious food in moderation, though it can trigger attacks in patients with systemic lupus erythematosus and large quantities can affect liver function and cause photosensitization[238]. A nutritional analysis is available[218]. An appetite-stimulating tea is made from the leaves[21, 55], it has a flavour somewhat reminiscent of boiled socks[144] and is slightly laxative[159]." [PFAF] "The leaves are eaten by the Chinese as a vegetable." [Sturtevant EPW]
- Health Beverge: "Health beverage manufactured from M. sativa buds was found benefiial in maintaining normal digestive function and nutrition balance in human body, reducing cholesterol, and preventing osteoporosis, arteriosclerosis and aging (Song & Wei, 2007)." [MedicagoSativa]
- Seed
- "Commonly used as a sprouted seed which is added to salads[2, 20, 52], used in sandwiches etc or cooked in soups[183]. The seed is soaked in warm water for 12 hours, then kept moist in a container in a warm place to sprout. It is ready in about 4 - 6 days[244]. The seeds can also be ground into a powder and used as a mush, or mixed with cereal flours for making a nutritionally improved bread etc[183, 213, 244]. Seed yields average around 186 - 280 kilos per hectare[269]. Native Americans ground the seed of related species to meal for baking and gruel." [PFAF]
- Sprouts: "A few years ago Alfalfa was something you fed to rabbits or cows, not humans, but Alfalfa seed sprouts are now an everyday food and can be found in almost all supermarkets. They are easy to produce; all you need is seed, water and a warm place. Soak the seeds overnight to hydrate them, and then keep them moist (but not wet), by rinsing them I - 3 times daily. When the sprouts are about an inch long, expose them to sunlight so they turn green, as this makes them more nutritious. They are usually ready to eat in 7 - 10 days." [????]
- "Medicago sativa (alfalfa) sprouts are commonly used as a source of protein." [SEHM]
- Oil: "Alfalfa seeds (M. sativa) contain only 7.8% of a highly unsaturated oil (Table 2.50) rich in carotenes and in lutein. It has been claimed that the seeds lower LDL cholesterol in patients with hyperlipoproteinemia and that the oil reduces erythema caused by sunburn (Firestone, 1996; Connock, website)." [CRC TLHB]
- Flavouring
- "Extract used as a flavor ingredient in most major categories of food products, including nonalcoholic and alcoholic beverages, frozen desserts, candy, baked goods, gelatins and puddings, and meat and meat products, with highest average maximum use level of 0.05% in the last category" [Leung ECNI]
- Used by Okanagan-Colville and Spokane to flavor foods being cooked in pits, as a sweetener. [NAEth Moerman]
- "Alfalfa is widely used in foods and is listed by the Council of Europe as a source of natural food flavouring (categories N2 and N3). These categories indicate that alfalfa can be added to foodstuffs in small quantities, with a possible limitation of an active principle (as yet unspecified) in the final product.(G16) Previously, alfalfa has been listed as GRAS (Generally Recognised As Safe).(G41)" [HerbalMed3]
Other Uses
"Alfalfa meal is used extensively as a poultry and cattle feed and as a source of raw material for the manufacture of leaf protein intended for human consumption. Alfalfa is also a source of chlorophyll manufacture." [Leung ECNI]
- Dye
- "A yellow dye is obtained from the seed[269]." [PFAF]
- Fibre
- "The fibre of the plant has been used in making paper[269]." [PFAF]
- Oil
- "The seed yields about 8.5 - 11% of a drying oil. It is used in paints, varnish etc[46, 57, 61, 269]." [PFAF]
Medicinal Uses
- Plant
- "Grown commercially as a source of chlorophyll and carotene, both of which have proven health benefits[222]. Extracts of the plant are antibacterial[218]. Used for asthma, diabetes, gastrointestinal disorders (anti-ulcer) [301].The plant is taken internally for debility in convalescence or anaemia, haemorrhage, menopausal complaints, pre-menstrual tension, fibroids etc[238]. The plant has an oestrogenic action and could prove useful in treating problems related to menstruation and the menopause[254]. The plant is antiscorbutic, aperient, diuretic, oxytocic, haemostatic, nutritive, stimulant and tonic[55, 165, 218]." [PFAF]
- Leaves
- "Alfalfa leaves, either fresh or dried, have traditionally been used as a nutritive tonic to stimulate the appetite and promote weight gain[222]. A poultice of the heated leaves has been applied to the ear in the treatment of earache[257]. The leaves can be used fresh or dried[238]. The leaves are rich in vitamin K which is used medicinally to encourage the clotting of blood[213]. This is valuable in the treatment of jaundice[213]. The leaves also contain the anti-oxidant tricin[222]." [PFAF]
- Leaves heated, held to ear for earache. (1)[ECIC Bocek]
- Juice
- "The expressed juice is emetic and is also anodyne in the treatment of gravel[218]." [PFAF]
- Root
- "The root is febrifuge and is also prescribed in cases of highly coloured urine[218]." [PFAF]
- "Xiong (2003) demonstrated that extracts prepared from M. sativa roots may be used to prepare medical preparations like powder, pill, or decoction for lowering the levels of cholesterol and lipid in blood, improving the liver function and the control and transmission of nerve tissue, and treating calculus." [MedicagoSativa]
- Aerial Parts
- "Parts used are the aerial parts. Reportedly used as a nutrient to increase vitality, appetite, and weight in humans; also as a diuretic, galactogogue, and to increase peristaltic action of the stomach and bowels, resulting in increased appetite; more recently for the treatment of asthma and hay fever (JIANGSU)." [Leung ECNI]
- Dermatological
- "The unsaponifiable extract has been claimed to be beneficial in treating skin conditions, including damage caused by radiotherapy and in the healing of gums after orthodontic operations.9 Alfalfa is also reportedly used in peelable facial masks (DE NAVARRE)" [Leung ECNI]
Dosages: Herb [HerbalMed3]
- "Dosages for oral administration (adults) for traditional uses recommended in older standard herbal reference texts are given below. "[HerbalMed3]
- "Dried herb 5–10 g as an infusion three times daily."[HerbalMed3]
- "Liquid extract 5–10 mL (1 : 1 in 25% alcohol) three times daily."[HerbalMed3]
Further Medicinal Use
"The present review emphasizes the phytochemical, traditional, pharmacological, clinical and toxicological reports on M. sativa. Saponins, flvonoids, phytoestrogens, coumarins, alkaloids, amino acids, phytosterols, vitamins, digestive enzymes and terpenes constitute major classes of phytoconstituents of the plant. M. sativa has been used since centuries as homoeopathic and Ayurvedic medicine for a variety of ailments. Th plant is widely used in foods and is listed by the Council of Europe as a source of natural food flvor (category N2 and N3). Thse categories indicate that M. sativa can be added to foodstuff in small quantities with a limitation on the concentrations of an active ingredient in the fial product. In the USA, M. sativa is listed as GRAS (generally recognized as safe). Recent research carried out indicates its uses such as neuroprotective, hypocholesterolemic, antioxidant, antiulcer, antimicrobial, hypolipidemic, immunopotentiating, estrogenic, digestive, nutritive for human body, and in the treatment of atherosclerosis, heart disease, stroke, cancer, diabetes and neurovegetative menopausal symptoms in women." [MedicagoSativa]
| Medicago sativa L. [CRNAH] | ||
| Source | Major Constituents | Therapeutic Values |
| China | Lucernol, sativol, coumesterol, formonetin, daidzein, tricin, citrulline, canaline, dicoumarol, methylenebishydroxy-coumarin, medicagemic acid, ononitol, petunidin, myrcene, malvidin, delphinidin, linalool, limonene.48 | Depurative, deobstruent, diuretic, stomachic, treat intestinal and kidney disorders, kidney stone, poor night vision. |
| North America | Isoflavones, coumarins, alkaloids, vitamins, porphyrins, stachydrine, l-homostarchydrine.100,102 | For menstruation and menopause. |
Arabs discovered the herb and named it al-facl-facah, or “father of all foods,” which the Spanish changed to “alfalfa.” It is rich in nutrients and minerals, including calcium, potassium, iron, magnesium, and zinc. A source of eight essential amino acids, alfalfa is used in China to treat fever, in India to treat ulcers, in Iraq and Turkey to treat arthritis, and in the U.S. in some natural therapies for cancer. It has also been employed for urinary infections, menopause, fatigue, and as an antibiotic and an antiasthmatic.[PDBHM]
"M. sativa has a long tradition of use as Ayurvedic and homoeopathic medicine in central nervous and digestive system disorders, and for the treatment of various other ailments." [MedicagoSativa]
"Traditionally, M. sativa is used to improve the memory, to cure kidney pain, cough, sore muscles, as a rejuvenator, antidiabetic, antioxidant, anti-inflmmatory, antifungal, anti-asthmatic, antimicrobial, diuretic, galactagogue and in central nervous system (CNS) disorders (Finkler, 1985; BHMA, 1996; Inamul, 2004; DerMarderosian et al., 2005). M. sativa has a long tradition of use as Ayurvedic and homoeopathic medicine in CNS disorders (Inamul, 2004). M. sativa has been used by the Chinese since the sixth century to treat kidney stones, fever, gravel, dysuria and to relieve fluid retention and swelling. Ancient Indian Ayurvedic physicians used M. sativa to treat ulcers, arthritis pain and fluid retention. In Mexico M. sativa is believed to improve the memory, to cure sore muscles and inflammation. Early Americans used M. sativa to treat arthritis, boils, cancer, scurvy, and urinary and bowel problems. In Iraq M. sativa is used in arthritis. In Turkey it is used as cardiotonic and to treat scurvy and arthritis (Michael et al., 2007; Finkler, 1985; Inamul, 2004; DerMarderosian et al., 2005).
Moreover, it is considered beneficial in bladder disorders, blood clotting disorders, boils, cough, diuresis, gastrointestinal tract disorders, breast cancer, cervical cancer, kidney disorders, prostate disorders, appetite stimulation, inflmmation, increasing breast milk, asthma, indigestion, insect bites, jaundice, menopausal symptoms, allergies, increasing excretion of neutral steroids and bile acids in fecal matter, nutritional support, stomach ulcers, skin damage from radiation, galactagogue, increasing peristaltic action of the stomach and bowels, thrombocytopenic purpura, uterine stimulant, rheumatoid arthritis, scurvy, vitamin supplementation (vitamins A, C, E, K) and wound healing (Gray & Flatt, 1997a, 1997b; BHMA, 1996; DerMarderosian et al., 2005; Swanston et al., 1990)." [MedicagoSativa]
Doses
- Preparations equivalent to 9–30 g dried aerial parts, per day (Mills, 1985; BHMA, 1983) [MedicagoSativa]
- Dried aerial parts: 5–10 g, 3 times per day (BHMA, 1983). 3–10 g, 3 times per day (Mills, 1985) [MedicagoSativa]
- Infusion: 5–10 g dried aerial parts, 3 times per day (BHMA, 1983) [MedicagoSativa]
- Fluid extract: 5–10 g dried equivalent, 3 times per day (BHMA, 1983) (1:1, 25% alcohol, 5–10 mL) [MedicagoSativa]
- Tablets: A dose of two tablets (1 g each) of Cholestaid™ (esterin processed M. sativa) taken by mouth 3 times daily for up to two months, then one tablet 3 times daily, has been recommended (Farnsworth, 1995). [MedicagoSativa]
- Seeds: For treating high cholesterol, a dose of 40 g of heated seeds taken by mouth 3 times daily has been recommended (Farnsworth, 1995). [MedicagoSativa]
Hazards
- Dermatitis: "Dermatitis has been recorded after the ingestion of infusions made from alfalfa seeds. Dermatitis has also been reported in horse handlers exposed to the straw itch mite, Pyemotes tritici, contaminating alfalfa seeds (55)." [SEHM]
Immunologic
Prolonged ingestion of alfalfa seeds or alfalfa tablets has been associated with the induction or exacerbation of a lupus-like syndrome in humans, perhaps because of the canavanine alfalfa contains (56,57).
Infection risk
Alfalfa seeds are readily infected and there have been numerous reports of infections arising from the consumption of alfalfa sprouts grown from contaminated seeds. The most common infections are with Salmonella species, including Salmonella enterica (58), Salmonella havana (59), Salmonella kottbus (60,61), Salmonella mbandaka (62), Salmonella muenchen (63), Salmonella paratyphi (64), Salmonella stanley (65), and other serotypes (66,67). Occasionally, other organisms occur, such as Listeria (68) and Escherichia coli (69,70).[SEHM]
Lore
Folk Names: Buffalo Herb, Lucerne, Purple Medic, Jat, Qadb
Gender: Feminine
Planet: Venus
Element: Earth
Powers: Prosperity, Anti-Hunger, Money
Magical Uses: Keep in the home to protect from poverty and hunger. It is best placed in a small jar in the cupboard or pantry. Also, burn alfalfa and scatter the ashes around the property for this purpose. Alfalfa is also used in money spells.[EMH Cunningham]
Phytochemicals
- "Acids Lauric acid, maleic acid, malic acid, malonic acid, myristic acid, oxalic acid, palmitic acid and quinic acid." [HerbalMed3]
- "Alkaloids Pyrrolidine-type (e.g. stachydrine, homostachydrine); pyridine-type (e.g. trigonelline) in the seeds only." [HerbalMed3]
- "Amino acids Arginine, asparagine (high concentration in seeds), cystine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan and valine. The non-protein toxic amino acid canavanine is present in leaves (0.9–1.2 mg/g), stems (0.6–0.9 mg/g) and seeds (5–14 mg/g)." [HerbalMed3]
- "Coumarins Medicagol." [HerbalMed3]
- "Isoflavonoids Coumestrol, biochanin A, daidzein, formononetin and genistein." [HerbalMed3]
- "Saponins 2–3%. Hydrolysis yields aglycones, medicagenic acid, soyasapogenols A–F and hederagenin.(1) Sugar chain components include arabinose, galactose, glucuronic acid, glucose, rhamnose and xylose." [HerbalMed3]
- "Steroids Campesterol, cycloartenol, b-sitosterol (major component), a-spinasterol and stigmasterol." [HerbalMed3]
- "Other constituents Carbohydrates (e.g. arabinose, fructose, sucrose, xylose), vitamins (A, B1, B6, B12, C, E, K), pectin methylesterase, pigments (e.g. chlorophyll, xanthophyll, b-carotene, anthocyanins), proteins, minerals and trace elements." [HerbalMed3]
"The manganese content of alfalfa (45.5 mg/kg) is reported to be the active principle responsible for a hypoglycaemic effect documented for the herb."[HerbalMed3]
"Claims have been made for it in the treatment of arthritis, high cholesterol, diabetes and peptic ulcers. Reputedly, the herb has bactericidal, cardiotonic, diuretic, emetic, emmenagogue and oestrogenic properties. Commercial preparations including teas, tablets and capsules are available. Alfalfa is stated to be a source of vitamins A, C, E and K, and of the minerals calcium, potassium, phosphorus and iron. It has been used for avitaminosis[vitamin deficiency] A, C, E or K, hypoprothrombinaemic purpura [impaired blood clotting], and debility of convalescence."[HerbalMed3]
"A major focus of biosynthetic studies of Leguminosae isoflavonoids has been to determine the pathways to phytoalexins such as the pterocarpan, (–)-medicarpin, and the isofl avan, (–)-vestitol. These are antifungal compounds synthesized de novo by the plant in response to fungal attack. Two species have been of particular importance in this work, the forage legume, alfalfa (Medicago sativa) and Lotus japonicus, respectively (Dixon, 1999; Dixon & Steele, 1999; Akashi et al., 2006a)." [Buelga RAPR]
"Phytoestrogens are found primarily in soy (Glycine max) as well as in forage legumes such as subterranean clover, red clover, and lucerne (alfalfa, Medicago sativa) that are cultivated widely around the world. These forage plants are the main sources of phytoestrogens in ruminant nutrition. Clovers and soy generally contain isofl avones, whereas lucerne contains coumestans."[Buelga RAPR]
Nutritional Information
"Alfalfa is stated to be a source of vitamins A, C, E and K, and of the minerals calcium, potassium, phosphorus and iron. It has been used for avitaminosis A, C, E or K, hypoprothrombinaemic purpura, and debility of convalescence.(G7, G64)" [HerbalMed3]
Pharmacology
- "Alfalfa saponins are hemolytic;[25] they also interfere with vitamin E metabolism and are believed to be one of the causes of ruminant bloat.[4,26] Alfalfa saponins are reported to be fungitoxic, antimicrobial, insecticidal, piscicidal, and taste repellent to rats, swine, and poultry, while attractive to rabbits." [Leung ECNI]
- "Medicagenic acid, isolated from the roots of alflafa, has shown potent in vitro inhibitory activity against medically pathogenic fungi.[27]" [Leung ECNI]
- "Saponins derived from the root of the plant have shown hypocholesterolemic activity in monkeys on a high cholesterol diet (also see quillaia).[30] Male rats fed a complex of alfalfa top saponins (1% of diet for 6 months) showed reduced levels of serum cholesterol and triglycerides, with no evidence of toxicity. Alfalfa top saponins have also shown hypocholesterolemic activity and prevention of atherosclerosis.[31]" [Leung ECNI]
- "The seeds are reported to contain trypsin inhibitors.(G41)" [HerbalMed3]
- "Reputedly, the herb has bactericidal, cardiotonic, diuretic, emetic, emmenagogue and oestrogenic properties.(2)" [HerbalMed3]
- "... canavanine, a nonprotein amino acid constituent which has been found to have Figure 2 Alfalfa – dried drug substance (herb). effects on human immunoregulatory cells in vitro.(14)" [HerbalMed3]
Mechanism
The coumarin and indanedione oral anticoagulants are vitamin K antagonists, which inhibit the enzyme vitamin K epoxide reductase so reducing the synthesis of vitamin K-dependent blood clotting factors by the liver. If the intake of dietary vitamin K1 increases, the synthesis of the blood clotting factors begins to return to normal. As a result the prothrombin time also begins to fall to its normal value. Naturally occurring vitamin K1 (phytomenadione) is found only in plants. The natural coumarins present in alfalfa are not considered to be anticoagulants, because they do not have the structural requirements for this activity.[HMI Stockey]
| Activities (Alfalfa) |
| "Abortifacient (f; MAD); Alterative (f; PED); Antiatherosclerotic (1; APA); Antibacterial (1; CRC; WOI); Antiinflammatory (f; APA); Antipyretic (f; PED); Antiscorbutic (1; CRC); Antispasmodic (f; PED); Antithrombic (f; PED); Aperitif (f; CRC; SKY); Bitter (f; PED); Cardiotonic (f; CRC); Choleretic (1; PNC); Cyanogenic (f; CRC); Deobstruent (f; CRC); Depurative (f; CRC; PED); Digestive (1; PED); Diuretic (1; CRC; PED; PH2); Ecbolic (f; CRC); Emetic (f; CRC); Emmenagogue (1; CRC; FNF; UPW); Estrogenic (1; CRC; FAD; SKY); Fungicide (1; FAD); Hemolytic (f; APA); Hemostat (f; FAD); Hypocholesterolemic (f; CAN; PED); Hypoglycemic (f; PED); Lactagogue (1; CRC; FNF; UPW); Stimulant (f; CRC); Stomachic (f; CRC; PED); Tonic (f; CRC; PED)." [HMH Duke] |
| Select Indications (Alfalfa) |
| Anorexia (f; CRC; FAD; SKY); Arthrosis (f; APA; CRC; FAD; MAD); Atherosclerosis (1; APA); Bacteria (1; CRC; FNF; WOI); Bleeding (f; FAD); Blood Clot (f; APA; PED); Cancer (f; FAD; JLH); Diabetes (1; APA; CAN; FAD; MAD; PH2); Dyspepsia (f; APA); Dysuria (f; CRC; PED); Enterosis (f; CRC); ERT (1; FAD; FNF; SKY); Fever (f; CRC; PED); High Cholesterol (1; APA; CAN; PED; PNC); Nephrosis (f; APA; CRC); Poor Milk Supply (1; FAD; FNF); Prostatosis (1; APA; FNF); Rheumatism (f; PED; MAD); Thyroidosis (f; PHR; PH2); Water Retention (1; CRC; PED; PH2); [HMH Duke] |
Nutritional Information
Alfalfa– Medicago sativa [218] [PFAF]
- Part: Leaves Per 100 g fresh weight
- Food Energy (Kcal) 52
- Riboflavin (mg)0.14
- Calcium (mg)12
- Water (g)82.70%
- Niacin (mg)0.5
- Phosphorus (mg)51
- Protein (g)6
- Vitamin C (mg)162
- Iron (mg)5.4
- Fat (g)0.4
- Ash (g)1.4
- Fiber (g)3.1
- Carbohydrate (g)9.5
- Thiamine (mg)0.13
Propagation
"Pre-soak the seed for 12 hours in warm water and then sow in spring in situ. The seed can also be sown in situ in autumn[52]. Seed can be obtained that has been inoculated with Rhizobium bacteria, enabling the plant to succeed in soils where the bacteria is not already present." [PFAF]
Cultivation
"Alfalfa is a very versatile plant that can adapt to a wide range of climatic conditions from cold temperate to warm sub-tropical.[269]. It succeeds on a wide variety of soils[52, 269], but thrives best on a rich, friable, well-drained loamy soil with loose topsoil supplied with lime[269]. It does not tolerate waterlogging and fails to grow on acid soils[269]. Grows well on light soils[206]. The plant has a deep taproot and, once establishd, tolerates drought and extremely dry conditions[52, 269]. Prefers a neutral fertile soil[87] but succeeds in relatively poor soils so long as the appropriate Rhizobium bacteria is present[200]. A good bee plant[46] and a food plant for many caterpillars[30]. Alfalfa is a very deep rooting plant, bringing up nutrients from deep in the soil and making them available for other plants with shallower root systems. It is a good companion plant for growing near fruit trees and grape vines so long as it is in a reasonably sunny position, but it does not grow well with onions or other members of the Allium genus[201]. Growing alfalfa encourages the growth of dandelions[201]. Alfalfa has long been cultivated for its edible seed, which can be sprouted and eaten in salads. It is also grown as a green manure and soil restorer. There are many named varieties[183]. Botanists divide the species into a number of sub-species - these are briefly described below:- M. sativa caerulea (Less. ex Ledeb.)Schmalh. This sub-species is likely to be of value in breeding programmes for giving cold tolerance, drought resistance and salt tolerance to alfalfa. M. sativa falcata (L.)Arcang. This sub-species is likely to be of value in breeding programmes for giving cold tolerance, drought and disease resistance plus salt and water-logging tolerance to alfalfa. M. sativa sativa. The commonly cultivated form of alfalfa. M. sativa varia (Martyn.)Arcang. This sub-species is likely to be of value in breeding programmes for giving cold tolerance, drought resistance and high yields to alfalfa. This species has a symbiotic relationship with certain soil bacteria, these bacteria form nodules on the roots and fix atmospheric nitrogen. Some of this nitrogen is utilized by the growing plant but some can also be used by other plants growing nearby[200]." [PFAF]
Green Manure: "Often grown as a green manure. It is a bit slow to establish in its first year so is generally only recommended for positions where it can remain for 2 or more years. Alfalfa is very vigorous from its second year, producing a huge bulk of material that can be cut down 2 or 3 times during the season[20, 87]." [PFAF]
Nitrogen Fixer: "Plants are very deep rooting, descending 6 metres or more into the soil[200], and are able to fix large quantities of atmospheric nitrogen, this makes them one of the very best green manures. Plants are rather intolerant of competition from grass etc, however, and there is the drawback of needing to leave them in the soil for more than 2 years to fully achieve their potential[K]." [PFAF]
Biomass: "Alfalfa is a potenially excellent source of biomass. It is possible to produce more than 2 tonnes of protein from the leaves (suitable for human use) per hectare per year. In addition, the plant residues remaining could be used to produce the equivalent of about 10 barrels of oil per year[269]." [PFAF]
Hedge: "The plant can be grown as a low dividing hedge in the vegetable garden[52, 206]." [PFAF]
Forage: "Domestic animals initially probably lived primarily from grazing wild plants. Since grazing commonly is not possible on a year-round basis, animals presumably lived over inclement periods, as now, on harvested food, probably hay harvested from the wild and seeds of the cultivated human-food cereals. Medicago was probably the first forage crop to be domesticated (Lesins and Lesins, 1979)" [Azolla Isely]
Misc
- An earlier publication (1) proved that tile addition of 0.1% of dehydrated alfalfa (Medicago sativa) to sea water before it was evaporated, prevented the production of scale in an evaporator if the 50% " blow down " principle was adhered to.[CDPSW Karl]
- Some mutations found in alfalfa (Medicago sativa L.) have a high capacity for resprouting after harvesting the basal branches.[EQUINT Mapes]
References
- [Azolla Isely] Leguminosae and Homo sapiens, DUANE ISELY, Economic Botany, 36(1), 1982
- [CDPSW Karl]Comparison of Dehydrated Plants in Their, Ability to Prevent Scale in a Sea-Water, Evaporator, HERMANN L. KARL AND BASIL TANNEL
- http://linnet.geog.ubc.ca/Atlas/Atlas.aspx?sciname=Medicago%20sativa&redblue=Both&lifeform=7 Accessed March 2, 2015
- [ECIC Bocek]Ethnobotany of Costanoan Indians, California, Based on Collections by John P. Harrington, BARBARAR. BOCEK, Economic Botany, 38(2), 1984
- [EQUINT Mapes]ETHNOBOTANY OF QUINTONIL: KNOWLEDGE, USE AND MANAGEMENT OF EDIBLE GREENSAMARANTHUSSPP. (AMARANTHACEAE) IN THE SIERRA NORTE DE PUEBLA, Mexico CRISTINA Mapes , FRANCISCO BASURTO, AND ROBERT BYE, Economic Botany 51(3) pp 293-306 1997
- http://www.pfaf.org/user/Plant.aspx?LatinName=Medicago+sativa, Accessed March 2, 2015